Antiplatelet treatment in patients with dengue and coronary artery disease:

clinical considerations and risks

Abstract

Dengue infection has increased in recent years and is currently a public health problem. Although the majority of those infected usually present asymptomatically or mildly, those who develop severe forms present potentially fatal complications, such as thrombotic and/or hemorrhagic events. That is why, in patients treated with antiplatelet agents, special caution must be taken. This is of special interest given the magnitude of the prevalence of coronary heart disease. Currently, there are no local guidelines for the management of antiplatelet therapy in these patients, however, certain factors must be considered when evaluating each patient: indication for antiplatelet treatment (primary versus secondary prevention), previous revascularization (recent or long-standing), and signs of bleeding and platelet count. A management algorithm is proposed according to these variables.