Cardiometabolic disease and FINDRISC score in patients with HIV in a South American hospital

Cardiometabolic disease in HIV

Abstract

Introduction: The presence of metabolic syndrome and the risk for diabetes in HIV-positive patients has been dismissed in South American patients. Objectives: To evaluate the frequency of metabolic syndrome and to compare the risk stratification for diabetes mellitus according to the FINDRISC in patients with HIV infection. Methodology: cross-sectional study of 760 HIV-infected adults in the period from January 2016 to December 2018. The presence of metabolic syndrome was evaluated through the ATP-III
criteria and the risk score for diabetes was examined according to the FINDRISC. Data obtained from medical records were correlated. In the inferential statistical analysis, odds ratios will be used as measures of association. In the case of numerical or quantitative variables, the Student's T or Mann-Whitney test was used.
Results: The most frequent comorbidity was smoking in 66.8%, second hypercholesterolemia (52%), third hypertension (32%). It was found that the FINDRISC found low risk in 646 patients (85%), moderate in 98 (12.8%), and high risk in 16 (2.2%). The presence of a high viral load and
a low CD4 count of less than 200 cells showed a statistical correlation with a moderately high FINDRISC. Conclusions: The present study showed a considerable frequency of patients with moderate and high risk of diabetes in patients with HIV infection. It is pertinent to consider cardiovascular risk factors and particularly the risk for the development of diabetes in patients with HIV.