Acute pulmonary thromboembolism in the Argentine Republic – 20th CONAREC Registry

Abstract

Introduction: Pulmonary embolism (PE) represents the third cause of cardiovascular death. However, there is lack of information about this entity in our country. Our aim was to describe baseline characteristics, clinical evolution and treatments for patients with acute PE in Argentina. Methods: Prospective multicentric registry which included patients with acute PE hospitalized in centers with cardiology residencies from October 2016 to November 2017. Conventional analysis was performed for descriptive and comparative statistics. A value of p<0.05 was considered significant. Cross audit was performed at 20% of participating centers. Results: We included 684 consecutive patients from 75 centers with an average age of 63.8 years, 56.7% of them being female. PE was reason for hospitalization in 70.8% of the cases. The most frequent predisposing factors were obesity, recent hospitalization, transient rest and active cancer. 96.8% received anticoagulation during hospitalization and reperfusion therapy was performed in 13.3% of patients. However, only 49% of patients with hemodynamic instability received any reperfusion therapy. Global in-hospital mortality was 12.3%, mainly related to PE. Conclusions: PE affects a heterogeneous group of patients with high in-hospital mortality mainly related to PE. We observed a low use of reperfusion therapies in patients with hemodynamic instability.