Ultra-rapid recovery in Takotsubo Syndrome: a case report

Authors

  • Víctor M Bósquez Mendoza Hospital de Especialidades del Centro Médico Nacional “Manuel Ávila Camacho “ del Instituto Mexicano del Seguro Social, Puebla, México
  • Carlos Bonilla Rodríguez Hospital de Especialidades del Centro Médico Nacional “Manuel Ávila Camacho “ del Instituto Mexicano del Seguro Social, Puebla, México https://orcid.org/0009-0009-4737-1902 (unauthenticated)
  • Ernesto Hernández Jiménez Hospital de Especialidades del Centro Médico Nacional “Manuel Ávila Camacho “ del Instituto Mexicano del Seguro Social, Puebla, México
  • María F Juárez Carmona Hospital de Especialidades del Centro Médico Nacional “Manuel Ávila Camacho “ del Instituto Mexicano del Seguro Social, Puebla, México https://orcid.org/0009-0001-1003-4904 (unauthenticated)

DOI:

https://doi.org/10.63600/ttzg0g81

Keywords:

Ultra-rapid recovery, Takotsubo syndrome, Stress-induced cardiomyopathy

Abstract

Takotsubo syndrome (TTS) is a transient cardiomyopathy characterized by acute ventricular dysfunction that mimics acute coronary syndrome, usually recovering within days to weeks. We present the case of a 45-year-old woman with cardiovascular risk factors who, after an emotional stress event, developed chest pain and ST-segment elevation, initially treated as acute myocardial infarction with thrombolysis without reperfusion. Coronary angiography revealed unobstructed epicardial arteries, and ventriculography showed the classic “apical ballooning” morphology. Remarkably, the patient achieved complete clinical, electrocardiographic, and echocardiographic recovery in less than 24 hours under conservative management. This outcome represents an unusually rapid course compared to the literature. Our report expands the clinical spectrum of TTS and highlights the importance of recognizing ultra-rapid presentations, as well as the need for multicenter studies to identify predictors of accelerated recovery

Author Biographies

  • Carlos Bonilla Rodríguez, Hospital de Especialidades del Centro Médico Nacional “Manuel Ávila Camacho “ del Instituto Mexicano del Seguro Social, Puebla, México

    Cardiólogo egresado del Hospital de Especialidades Puebla.

  • Ernesto Hernández Jiménez, Hospital de Especialidades del Centro Médico Nacional “Manuel Ávila Camacho “ del Instituto Mexicano del Seguro Social, Puebla, México

    Cardiólogo Clínico egresado de Instituto Mexicano del Seguro Social, Hospital de la Raza, Ciudad de México, México.

    Tutor del Curso de Cardiología del Instituto Mexicano del Seguro Social, Hospital de Especialidades Puebla, México

  • María F Juárez Carmona , Hospital de Especialidades del Centro Médico Nacional “Manuel Ávila Camacho “ del Instituto Mexicano del Seguro Social, Puebla, México

    Cardióloga del Hospital de Especialidades Puebla, México

References

1. Sato H, Tateishi H, Uchida T. Takotsubo-type cardiomyopathy due to multivessel spasm. In: Kodama K, Haze K, Hon M, editors. Clinical aspect of myocardial injury: From ischemia to heart failure. Tokyo: Kagakuhyouronsya; 1990. p. 56–64.

2. Templin C, Ghadri JR, Diekmann J, Napp LC, Bataiosu DR, Jaguszewski M, et al. Clinical features and outcomes of Takotsubo (stress) cardiomyopathy. N Engl J Med. 2015;373(10):929–38.

3. Lyon AR, Bossone E, Schneider B, Sechtem U, Citro R, Underwood SR, et al. Current state of knowledge on Takotsubo syndrome: A Position Statement from the Taskforce on Takotsubo Syndrome of the Heart Failure Association of the ESC. Eur J Heart Fail. 2016;18(1):8–27.

4. Pelliccia F, Kaski JC, Crea F, Camici PG. Pathophysiology of Takotsubo Syndrome. Circulation. 2017;135(24):2426–41.

5. Gianni M, Dentali F, Grandi AM, Sumner G, Hiralal R, Lonn E. Apical ballooning syndrome or takotsubo cardiomyopathy: a systematic review. Eur Heart J. 2006;27(13):1523–9.

6. Prasad A, Lerman A, Rihal CS. Apical ballooning syndrome (Takotsubo or stress cardiomyopathy): A mimic of acute myocardial infarction. Am Heart J. 2008;155(3):408–17.

7. Deshmukh A, Kumar G, Pant S, Rihal C, Murugiah K, Mehta JL. Prevalence of Takotsubo cardiomyopathy in the United States. Am Heart J. 2012;164(1):66–71.e1.

8. Jurisic S, Gili S, Cammann VL, Kato K, Szawan KA, D’Ascenzo F, y cols. Clinical predictors and prognostic impact of recovery of wall motion abnormalities in Takotsubo syndrome: Results from the International Takotsubo Registry. J Am Heart Assoc. 2019;8(21):e011194. doi:10.1161/JAHA.118.011194.

9. Bybee KA, Prasad A. Stress-related cardiomyopathy syndromes. Circulation. 2008;118(4):397–409.

10. Ghadri JR, Wittstein IS, Prasad A, Sharkey S, Dote K, Akashi YJ, et al. International expert consensus document on Takotsubo syndrome (Part I): Clinical characteristics, diagnostic criteria, and pathophysiology. Eur Heart J. 2018;39(22):2032–46.

Published

2026-06-30

How to Cite

1.
Ultra-rapid recovery in Takotsubo Syndrome: a case report. Rev. Fed. Arg. Cardiol. [Internet]. 2026 Jun. 30 [cited 2026 Sep. 26];55(2):143-5. Available from: https://revistafac.org.ar/ojs/index.php/revistafac/article/view/753